DC260126: A Small-Molecule Antagonist of GPR40 that Protects against Pancreatic β-Cells Dysfunction in db/db Mice

G protein-coupled receptor 40 (GPR40) mediates both acute and chronic effects of free fatty acids (FFAs) on insulin secretion. However, it remains controversial whether inhibition of GPR40 would be beneficial in prevention of type 2 diabetes. This study is designed to evaluate the potential effects...

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Detalhes bibliográficos
Main Authors: Sun, Peng, Wang, Ting, Zhou, Yuren, Liu, Hong, Jiang, Hualiang, Zhu, Weiliang, Wang, Heyao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679087/
https://ncbi.nlm.nih.gov/pubmed/23776696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066744
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