Evidence for NADPH oxidase activation by GPR40 in pancreatic β-cells

Objective: Investigate the involvement of the fatty acids receptor GPR40 in the assembly and activation of NADPH oxidase and the implications on pancreatic β-cell function. Methods: BRIN-BD11 β-cells were exposed to GPR40 agonist (GW9508) or linoleic acid in different glucose concentrations. Superox...

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Publicat a:Redox Rep
Autors principals: Nunes Marsiglio-Librais, Gabriela, Aparecida Vilas-Boas, Eloisa, Carlein, Christopher, Hoffmann, Markus Daniel Alexander, Roma, Leticia Prates, Carpinelli, Angelo Rafael
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2020
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7241480/
https://ncbi.nlm.nih.gov/pubmed/32354273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13510002.2020.1757877
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