Epitope Mapping of M36, a Human Antibody Domain with Potent and Broad HIV-1 Inhibitory Activity

M36 is the first member of a novel class of potent HIV-1 entry inhibitors based on human engineered antibody domains (eAds). It exhibits broad inhibitory activity suggesting that its CD4-induced epitope is highly conserved. Here, we describe fine mapping of its epitope by using several approaches. F...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Wan, Chao, Sun, Jianping, Chen, Weizao, Yuan, Xiaohui, Chong, Huihui, Prabakaran, Ponraj, Dimitrov, Dimiter S., He, Yuxian
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2013
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679054/
https://ncbi.nlm.nih.gov/pubmed/23776690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066638
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