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Bifunctional fusion proteins of the human engineered antibody domain m36 with human soluble CD4 are potent inhibitors of diverse HIV-1 isolates

Currently used antiretroviral therapy is highly successful but there is still a need for new effective and safe prophylactics and therapeutics. We have previously identified and characterized a human engineered antibody domain (eAd), m36, which exhibits potent broadly neutralizing activity against H...

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Autors principals: Chen, Weizao, Xiao, Xiaodong, Wang, Yanping, Zhu, Zhongyu, Dimitrov, Dimiter S.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954370/
https://ncbi.nlm.nih.gov/pubmed/20709110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2010.08.004
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