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A large human domain antibody library combining heavy and light chain CDR3 diversity
Domain antibodies (dAbs) are promising candidate therapeutics and diagnostics. Efficient selection of novel potent dAbs with potential for clinical utility is critically dependent on the library diversity and size, and the scaffold stability. We have previously constructed a large (size ~ 2.5 × 10(1...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2841289/ https://ncbi.nlm.nih.gov/pubmed/19883941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2009.09.039 |
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