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A large human domain antibody library combining heavy and light chain CDR3 diversity
Domain antibodies (dAbs) are promising candidate therapeutics and diagnostics. Efficient selection of novel potent dAbs with potential for clinical utility is critically dependent on the library diversity and size, and the scaffold stability. We have previously constructed a large (size ~ 2.5 × 10(1...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2841289/ https://ncbi.nlm.nih.gov/pubmed/19883941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2009.09.039 |
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