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Secondary Genomic Rearrangements Involving Immunoglobulin or MYC Loci Show Similar Prevalences in Hyperdiploid and Nonhyperdiploid Myeloma Tumors
The pathogenesis of multiple myeloma (MM) is thought to involve at least two pathways, which generate hyperdiploid (HRD) or nonhyperdiploid (NHRD) tumors, respectively. Apart from chromosome content, the two pathways are distinguished by five primary immunoglobulin heavy chain (IGH) rearrangements (...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3678755/ https://ncbi.nlm.nih.gov/pubmed/18381641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.20563 |
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