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Secondary Genomic Rearrangements Involving Immunoglobulin or MYC Loci Show Similar Prevalences in Hyperdiploid and Nonhyperdiploid Myeloma Tumors

The pathogenesis of multiple myeloma (MM) is thought to involve at least two pathways, which generate hyperdiploid (HRD) or nonhyperdiploid (NHRD) tumors, respectively. Apart from chromosome content, the two pathways are distinguished by five primary immunoglobulin heavy chain (IGH) rearrangements (...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gabrea, Ana, Martelli, Maria Luisa, Qi, Ying, Roschke, Anna, Barlogie, Bart, Shaughnessy, John D., Sawyer, Jeffrey R., Kuehl, W. Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678755/
https://ncbi.nlm.nih.gov/pubmed/18381641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.20563
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