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Secondary Genomic Rearrangements Involving Immunoglobulin or MYC Loci Show Similar Prevalences in Hyperdiploid and Nonhyperdiploid Myeloma Tumors

The pathogenesis of multiple myeloma (MM) is thought to involve at least two pathways, which generate hyperdiploid (HRD) or nonhyperdiploid (NHRD) tumors, respectively. Apart from chromosome content, the two pathways are distinguished by five primary immunoglobulin heavy chain (IGH) rearrangements (...

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Bibliografische gegevens
Hoofdauteurs: Gabrea, Ana, Martelli, Maria Luisa, Qi, Ying, Roschke, Anna, Barlogie, Bart, Shaughnessy, John D., Sawyer, Jeffrey R., Kuehl, W. Michael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678755/
https://ncbi.nlm.nih.gov/pubmed/18381641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.20563
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