Diverse karyotypic abnormalities of the c-myc locus associated with c-myc dysregulation and tumor progression in multiple myeloma

Translocations involving c-myc and an Ig locus have been reported rarely in human multiple myeloma (MM). Using specific fluorescence in situ hybridization probes, we show complex karyotypic abnormalities of the c-myc or L-myc locus in 19 of 20 MM cell lines and approximately 50% of advanced primary...

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Hlavní autoři: Shou, Yaping, Martelli, Maria L., Gabrea, Ana, Qi, Ying, Brents, Leslie A., Roschke, Anna, Dewald, Gordon, Kirsch, Ilan R., Bergsagel, P. Leif, Kuehl, W. Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2000
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC26645/
https://ncbi.nlm.nih.gov/pubmed/10618400
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