Immunoglobulin free light chains and GAGs mediate Multiple Myeloma Extracellular Vesicles uptake and secondary NfkB nuclear translocation

Multiple Myeloma (MM) is a hematological malignancy caused by a microenviromentally-aided persistence of plasma cells in the bone marrow. Monoclonal plasma cells often secrete high amounts of immunoglobulin free light chains (FLCs) that could induce tissue damage. Recently we showed that FLCs are in...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Giuseppe eDi Noto, Marco eChiarini, Lucia ePaolini, Elena eMazzoldi, Viviana eGiustini, Annalisa eRadeghieri, Luigi eCaimi, Doris eRicotta
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2014-10-01
Цуврал:	Frontiers in Immunology
Нөхцлүүд:	Multiple Myeloma NFkB extracellular vesicles serum Free Light Chain Glycosaminoglicans
Онлайн хандалт:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00517/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!