Multipotent mesenchymal stromal cells decrease transforming growth factor β1 expression in microglia/macrophages and down-regulate plasminogen activator inhibitor 1 expression in astrocytes after stroke

Multipotent mesenchymal stromal cells (MSCs) decrease the expression of transforming growth factor β1 (TGFβ1) in astrocytes and subsequently decrease astrocytic plasminogen activator inhibitor 1 (PAI-1) level in an autocrine manner. Since activated microglia/macrophages are also a source of TGFβ1 af...

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Hlavní autoři: Xin, Hongqi, Chopp, Michael, Shen, Li Hong, Zhang, Rui Lan, Zhang, Li, Zhang, Zheng Gang, Li, Yi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678739/
https://ncbi.nlm.nih.gov/pubmed/23499476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2013.02.046
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