Increasing tPA Activity in Astrocytes Induced by Multipotent Mesenchymal Stromal Cells Facilitate Neurite Outgrowth after Stroke in the Mouse

We demonstrate that tissue plasminogen activator (tPA) and its inhibitors contribute to neurite outgrowth in the central nervous system (CNS) after treatment of stroke with multipotent mesenchymal stromal cells (MSCs). In vivo, administration of MSCs to mice subjected to middle cerebral artery occlu...

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Detalhes bibliográficos
Main Authors: Xin, Hongqi, Li, Yi, Shen, Li Hong, Liu, Xianshuang, Wang, Xinli, Zhang, Jing, Pourabdollah-Nejad D, Siamak, Zhang, Chunling, Zhang, Li, Jiang, Hao, Zhang, Zheng Gang, Chopp, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815778/
https://ncbi.nlm.nih.gov/pubmed/20140248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009027
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