Secondary Release of Exosomes from Astrocytes Contributes to the Increase in Neural Plasticity and Improvement of Functional Recovery after Stroke in Rats Treated with Exosomes Harvested from MicroRNA 133b-Overexpressing Multipotent Mesenchymal Stromal Cells

We previously demonstrated that multipotent mesenchymal stromal cells (MSCs) that overexpress microRNA 133b (miR-133b) significantly improve functional recovery in rats subjected to middle cerebral artery occlusion (MCAO) compared with naive MSCs and that exosomes generated from naive MSCs mediate t...

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Detalhes bibliográficos
Publicado no:Cell Transplant
Main Authors: Xin, Hongqi, Wang, Fengjie, Li, Yanfeng, Lu, Qing-E, Cheung, Wing Lee, Zhang, Yi, Zhang, Zheng Gang, Chopp, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5303172/
https://ncbi.nlm.nih.gov/pubmed/27677799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096368916X693031
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