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MiR-133b promotes neural plasticity and functional recovery after treatment of stroke with multipotent mesenchymal stromal cells in rats via transfer of exosome-enriched extracellular particles

To test, in vivo, the hypothesis that exosomes from multipotent mesenchymal stromal cells (MSCs) mediate microRNA 133b (miR-133b) transfer which promotes neurological recovery from stroke, we employed knock-in and knock-down technologies to up-regulate or down-regulate the miR-133b level in MSCs (mi...

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Detalhes bibliográficos
Main Authors: Xin, Hongqi, Li, Yi, Liu, Zhongwu, Wang, Xinli, Shang, Xia, Cui, Yisheng, Zhang, Zheng Gang, Chopp, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3788061/
https://ncbi.nlm.nih.gov/pubmed/23630198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1409
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