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MiR-133b promotes neural plasticity and functional recovery after treatment of stroke with multipotent mesenchymal stromal cells in rats via transfer of exosome-enriched extracellular particles
To test, in vivo, the hypothesis that exosomes from multipotent mesenchymal stromal cells (MSCs) mediate microRNA 133b (miR-133b) transfer which promotes neurological recovery from stroke, we employed knock-in and knock-down technologies to up-regulate or down-regulate the miR-133b level in MSCs (mi...
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Glavni autori: | , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2013
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3788061/ https://ncbi.nlm.nih.gov/pubmed/23630198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1409 |
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