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Neurofibrillary Tangle-Like Tau Pathology Induced by Synthetic Tau Fibrils in Primary Neurons Over-expressing Mutant Tau

Increasing evidence demonstrates the transmissibility of fibrillar species of tau protein, but this has never been directly tested in neurons, the cell type most affected by formation of tau inclusions in neurodegenerative tauopathies. Here we show that synthetic tau fibrils made from recombinant pr...

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Autors principals: Guo, Jing L., Lee, Virginia M.Y.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678381/
https://ncbi.nlm.nih.gov/pubmed/23395797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2013.01.051
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