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Neurofibrillary Tangle-Like Tau Pathology Induced by Synthetic Tau Fibrils in Primary Neurons Over-expressing Mutant Tau
Increasing evidence demonstrates the transmissibility of fibrillar species of tau protein, but this has never been directly tested in neurons, the cell type most affected by formation of tau inclusions in neurodegenerative tauopathies. Here we show that synthetic tau fibrils made from recombinant pr...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3678381/ https://ncbi.nlm.nih.gov/pubmed/23395797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2013.01.051 |
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