Synthetic Tau Fibrils Mediate Transmission of Neurofibrillary Tangles in a Transgenic Mouse Model of Alzheimer's-Like Tauopathy

Tauopathies, including Alzheimer's disease (AD) and frontotemporal lobar degeneration with tau pathologies, are neurodegenerative diseases characterized by neurofibrillary tangles (NFTs) comprising filamentous tau protein. Although emerging evidence suggests that tau pathology may be transmitte...

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Autores principales: Iba, Michiyo, Guo, Jing L., McBride, Jennifer D., Zhang, Bin, Trojanowski, John Q., Lee, Virginia M.-Y.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2013
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575082/
https://ncbi.nlm.nih.gov/pubmed/23325240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2642-12.2013
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