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RRE-deleting self-inactivating and self-activating HIV-1 vectors for improved safety

Retroviruses have been shown to efficiently delete sequences between repeats as a consequence of the template switching ability of the viral reverse transcriptase. To evaluate this approach for deriving safety-modified lentiviral vectors, we created HIV-1 vectors engineered to delete the Rev-respons...

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書目詳細資料
主要作者: Srinivasakumar, Narasimhachar
格式: Artigo
語言:Inglês
出版: PeerJ Inc. 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678115/
https://ncbi.nlm.nih.gov/pubmed/23761857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.84
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