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Rev–RRE Functional Activity Differs Substantially Among Primary HIV-1 Isolates

The HIV-1 replication cycle requires the nucleocytoplasmic export of intron-containing viral RNAs, a process that is ordinarily restricted. HIV overcomes this by means of the viral Rev protein, which binds to an RNA secondary structure called the Rev response element (RRE) present in all unspliced o...

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Detalhes bibliográficos
Publicado no:AIDS Res Hum Retroviruses
Main Authors: Jackson, Patrick E., Tebit, Denis M., Rekosh, David, Hammarskjold, Marie-Louise
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028908/
https://ncbi.nlm.nih.gov/pubmed/27147495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2016.0047
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