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RRE-deleting self-inactivating and self-activating HIV-1 vectors for improved safety

Retroviruses have been shown to efficiently delete sequences between repeats as a consequence of the template switching ability of the viral reverse transcriptase. To evaluate this approach for deriving safety-modified lentiviral vectors, we created HIV-1 vectors engineered to delete the Rev-respons...

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Detalhes bibliográficos
Autor principal: Srinivasakumar, Narasimhachar
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678115/
https://ncbi.nlm.nih.gov/pubmed/23761857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.84
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