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RRE-deleting self-inactivating and self-activating HIV-1 vectors for improved safety
Retroviruses have been shown to efficiently delete sequences between repeats as a consequence of the template switching ability of the viral reverse transcriptase. To evaluate this approach for deriving safety-modified lentiviral vectors, we created HIV-1 vectors engineered to delete the Rev-respons...
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| Hlavní autor: | |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
PeerJ Inc.
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3678115/ https://ncbi.nlm.nih.gov/pubmed/23761857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.84 |
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