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Substitution of the Rev-response element in an HIV-1-based gene delivery system with that of SIVmac239 allows efficient delivery of Rev M10 into T-lymphocytes

BACKGROUND: Human immunodeficiency virus type 1 (HIV-1)-based gene delivery systems are popular due to their superior efficiency of transduction of primary cells. However, these systems cannot be readily used for delivery of anti-HIV-1 genes that target constituents of the packaging system itself du...

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Autore principale: Srinivasakumar, Narasimhachar
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438438/
https://ncbi.nlm.nih.gov/pubmed/18534033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-6405-5-11
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