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Real Time Measures of Prestin Charge and Fluorescence during Plasma Membrane Trafficking Reveal Sub-Tetrameric Activity

Prestin (SLC26a5) is the outer hair cell integral membrane motor protein that drives cochlear amplification, and has been described as an obligate tetramer. We studied in real time the delivery of YFP-prestin to the plasma membrane of cells from a tetracycline-inducible cell line. Following the rele...

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Autori principali: Bian, Shumin, Navaratnam, Dhasakumar, Santos-Sacchi, Joseph
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677934/
https://ncbi.nlm.nih.gov/pubmed/23762468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066078
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