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A highly expressing Tet-inducible cell line recapitulates in situ developmental changes in prestin's Boltzmann characteristics and reveals early maturational events

Prestin is the motor protein within the lateral membrane of outer hair cells (OHCs), and it is required for mammalian cochlear amplification. Expression of prestin precedes the onset of hearing in mice, and it has been suggested that prestin undergoes a functional maturation within the membrane coin...

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Main Authors: Bian, Shumin, Koo, Bon W., Kelleher, Stephen, Santos-Sacchi, Joseph, Navaratnam, Dhasakumar S.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774197/
https://ncbi.nlm.nih.gov/pubmed/20631244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00182.2010
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