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Tyrosine motifs are required for prestin basolateral membrane targeting

Prestin is targeted to the lateral wall of outer hair cells (OHCs) where its electromotility is critical for cochlear amplification. Using MDCK cells as a model system for polarized epithelial sorting, we demonstrate that prestin uses tyrosine residues, in a YXXΦ motif, to target the basolateral sur...

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Dades bibliogràfiques
Publicat a:Biol Open
Autors principals: Zhang, Yifan, Moeini-Naghani, Iman, Bai, JunPing, Santos-Sacchi, Joseph, Navaratnam, Dhasakumar S.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365488/
https://ncbi.nlm.nih.gov/pubmed/25596279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.201410629
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