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Tyrosine motifs are required for prestin basolateral membrane targeting

Prestin is targeted to the lateral wall of outer hair cells (OHCs) where its electromotility is critical for cochlear amplification. Using MDCK cells as a model system for polarized epithelial sorting, we demonstrate that prestin uses tyrosine residues, in a YXXΦ motif, to target the basolateral sur...

詳細記述

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書誌詳細
出版年:Biol Open
主要な著者: Zhang, Yifan, Moeini-Naghani, Iman, Bai, JunPing, Santos-Sacchi, Joseph, Navaratnam, Dhasakumar S.
フォーマット: Artigo
言語:Inglês
出版事項: The Company of Biologists 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365488/
https://ncbi.nlm.nih.gov/pubmed/25596279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.201410629
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