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Regulation of T cell function by the ubiquitin-specific protease USP9X via modulating the Carma1-Bcl10-Malt1 complex

The ubiquitin conjugation system plays an important role in immune regulation; however, the ubiquitin-specific proteases (USPs) that carry out deubiquitination of cellular substrates are poorly understood. Here we show that in vivo knockdown of the deubiquitinating enzyme USP9X attenuates T-cell pro...

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Autors principals: Park, Yoon, Jin, Hyung-seung, Liu, Yun-Cai
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677447/
https://ncbi.nlm.nih.gov/pubmed/23690623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221925110
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