Mature T-cell Lymphomagenesis Induced by Retroviral Insertional Activation of Janus Kinase 1

Retroviral vectors (RVs) are powerful tools in clinical gene therapy. However, stable genomic integration of RVs can be oncogenic, as reported in several animal models and in clinical trials. Previously, we observed that T-cell receptor (TCR) polyclonal mature T cells are resistant to transformation...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Heinrich, Tim, Rengstl, Benjamin, Muik, Alexander, Petkova, Mina, Schmid, Frederike, Wistinghausen, Robin, Warner, Kathrin, Crispatzu, Giuliano, Hansmann, Martin-Leo, Herling, Marco, von Laer, Dorothee, Newrzela, Sebastian
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2013
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677306/
https://ncbi.nlm.nih.gov/pubmed/23609016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.67
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki