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What Renders TAU Toxic

TAU is a microtubule-associated protein that under pathological conditions such as Alzheimer’s disease (AD) forms insoluble, filamentous aggregates. When 20 years after TAU’s discovery the first TAU transgenic mouse models were established, one declared goal that was achieved was the modeling of aut...

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Detalhes bibliográficos
Main Authors: Götz, Jürgen, Xia, Di, Leinenga, Gerhard, Chew, Yee Lian, Nicholas, Hannah R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677143/
https://ncbi.nlm.nih.gov/pubmed/23772223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2013.00072
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