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PTL-1 regulates neuronal integrity and lifespan in C. elegans

Protein with tau-like repeats (PTL-1) is the sole Caenorhabditis elegans homolog of tau and MAP2, which are members of the mammalian family of microtubule-associated proteins (MAPs). In mammalian neurons, tau and MAP2 are segregated, with tau being mainly localised to the axon and MAP2 mainly to the...

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Detalhes bibliográficos
Main Authors: Chew, Yee Lian, Fan, Xiaochen, Götz, Jürgen, Nicholas, Hannah R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068611/
https://ncbi.nlm.nih.gov/pubmed/23525010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.jcs124404
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