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Regulation of age-related structural integrity in neurons by protein with tau-like repeats (PTL-1) is cell autonomous
PTL-1 is the sole homolog of the MAP2/MAP4/tau family in Caenorhabditis elegans. Accumulation of tau is a pathological hallmark of neurodegenerative diseases such as Alzheimer's disease. Therefore, reducing tau levels has been suggested as a therapeutic strategy. We previously showed that PTL-1...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4046136/ https://ncbi.nlm.nih.gov/pubmed/24898126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05185 |
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