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What Renders TAU Toxic

TAU is a microtubule-associated protein that under pathological conditions such as Alzheimer’s disease (AD) forms insoluble, filamentous aggregates. When 20 years after TAU’s discovery the first TAU transgenic mouse models were established, one declared goal that was achieved was the modeling of aut...

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Autors principals: Götz, Jürgen, Xia, Di, Leinenga, Gerhard, Chew, Yee Lian, Nicholas, Hannah R.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677143/
https://ncbi.nlm.nih.gov/pubmed/23772223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2013.00072
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