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Effect of ABCB1 polymorphisms and atorvastatin on sitagliptin pharmacokinetics in healthy volunteers

OBJECTIVES: The objectives of this study were to determine if ABCB1 polymorphisms are associated with interindividual variability in sitagliptin pharmacokinetics, and if atorvastatin alters the pharmacokinetic disposition of sitagliptin in healthy volunteers. METHODS: In this open-label, randomized,...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Aquilante, Christina L., Wempe, Michael F., Sidhom, Maha S., Kosmiski, Lisa A., Predhomme, Julie A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676426/
https://ncbi.nlm.nih.gov/pubmed/23407853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-013-1475-y
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