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Chronic Hypoxia Impairs Cytochrome Oxidase Activity Via Oxidative Stress in Selected Fetal Guinea Pig Organs

We hypothesized that chronic hypoxia disrupts mitochondrial function via oxidative stress in fetal organs. Pregnant guinea pig sows were exposed to either normoxia or hypoxia (10.5% O(2), 14 days) in the presence or absence of the antioxidant, N-acetylcysteine (NAC). Near-term anesthetized fetuses w...

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Main Authors: Al-Hasan, Yazan M., Evans, LaShauna C., Pinkas, Gerard A., Dabkowski, Erinne R., Stanley, William C., Thompson, Loren P.
Formato: Artigo
Idioma:Inglês
Publicado: SAGE Publications 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676261/
https://ncbi.nlm.nih.gov/pubmed/22923417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719112453509
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