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Chronic Hypoxia Impairs Cytochrome Oxidase Activity Via Oxidative Stress in Selected Fetal Guinea Pig Organs

We hypothesized that chronic hypoxia disrupts mitochondrial function via oxidative stress in fetal organs. Pregnant guinea pig sows were exposed to either normoxia or hypoxia (10.5% O(2), 14 days) in the presence or absence of the antioxidant, N-acetylcysteine (NAC). Near-term anesthetized fetuses w...

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書誌詳細
主要な著者: Al-Hasan, Yazan M., Evans, LaShauna C., Pinkas, Gerard A., Dabkowski, Erinne R., Stanley, William C., Thompson, Loren P.
フォーマット: Artigo
言語:Inglês
出版事項: SAGE Publications 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676261/
https://ncbi.nlm.nih.gov/pubmed/22923417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719112453509
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