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Prenatal Nicotine Increases Matrix Metalloproteinase 2 (MMP-2) Expression in Fetal Guinea Pig Hearts

This study tested the hypothesis that maternal nicotine ingestion increases matrix metalloproteinase (MMP) expression in fetal hearts, which is mediated by the generation of reactive oxygen species. Timed pregnant guinea pigs were administered either water alone, nicotine (200 μg/mL), N-acetylcystei...

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Detalhes bibliográficos
Main Authors: Thompson, Loren P., Liu, Hongshan, Evans, LaShauna, Mong, Jessica A.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343142/
https://ncbi.nlm.nih.gov/pubmed/21775771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719111404605
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