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Chronic Hypoxia Impairs Cytochrome Oxidase Activity Via Oxidative Stress in Selected Fetal Guinea Pig Organs

We hypothesized that chronic hypoxia disrupts mitochondrial function via oxidative stress in fetal organs. Pregnant guinea pig sows were exposed to either normoxia or hypoxia (10.5% O(2), 14 days) in the presence or absence of the antioxidant, N-acetylcysteine (NAC). Near-term anesthetized fetuses w...

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Bibliografiska uppgifter
Huvudupphovsmän: Al-Hasan, Yazan M., Evans, LaShauna C., Pinkas, Gerard A., Dabkowski, Erinne R., Stanley, William C., Thompson, Loren P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: SAGE Publications 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676261/
https://ncbi.nlm.nih.gov/pubmed/22923417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719112453509
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