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Transcription Factor Nrf2-Mediated Antioxidant Defense System in the Development of Diabetic Retinopathy
PURPOSE. Increase in reactive oxygen species (ROS) is one of the major retinal metabolic abnormalities associated with the development of diabetic retinopathy. NF-E2–related factor 2 (Nrf2), a redox sensitive factor, provides cellular defenses against the cytotoxic ROS. In stress conditions, Nrf2 di...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Association for Research in Vision and Ophthalmology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3676188/ https://ncbi.nlm.nih.gov/pubmed/23633659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-11598 |
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