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Long Noncoding RNA MALAT1 and Regulation of the Antioxidant Defense System in Diabetic Retinopathy

The retina experiences increased oxidative stress in diabetes, and the transcriptional activity of Nrf2, which is critical in regulating many antioxidant genes, is decreased. The nuclear movement/transcriptional activity of Nrf2 is mediated by its intracellular inhibitor Keap1, and retinal Keap1 lev...

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Bibliografiske detaljer
Udgivet i:Diabetes
Main Authors: Radhakrishnan, Rakesh, Kowluru, Renu A.
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7881848/
https://ncbi.nlm.nih.gov/pubmed/33051272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db20-0375
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