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Transcription Factor Nrf2-Mediated Antioxidant Defense System in the Development of Diabetic Retinopathy
PURPOSE. Increase in reactive oxygen species (ROS) is one of the major retinal metabolic abnormalities associated with the development of diabetic retinopathy. NF-E2–related factor 2 (Nrf2), a redox sensitive factor, provides cellular defenses against the cytotoxic ROS. In stress conditions, Nrf2 di...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Association for Research in Vision and Ophthalmology
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3676188/ https://ncbi.nlm.nih.gov/pubmed/23633659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-11598 |
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