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The N Terminus of Andes Virus L Protein Suppresses mRNA and Protein Expression in Mammalian Cells

Little is known about the structure and function of the 250-kDa L protein of hantaviruses, although it plays a central role in virus genome transcription and replication. When attempting to study Andes virus (ANDV) L protein in mammalian cells, we encountered difficulties. Even in a strong overexpre...

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Detalhes bibliográficos
Main Authors: Heinemann, Patrick, Schmidt-Chanasit, Jonas, Günther, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676134/
https://ncbi.nlm.nih.gov/pubmed/23576516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00043-13
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