The 3′ Untranslated Region of the Andes Hantavirus Small mRNA Functionally Replaces the Poly(A) Tail and Stimulates Cap-Dependent Translation Initiation from the Viral mRNA

In the process of translation of eukaryotic mRNAs, the 5′ cap and the 3′ poly(A) tail interact synergistically to stimulate protein synthesis. Unlike its cellular counterparts, the small mRNA (SmRNA) of Andes hantavirus (ANDV), a member of the Bunyaviridae, lacks a 3′ poly(A) tail. Here we report th...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Vera-Otarola, Jorge, Soto-Rifo, Ricardo, Ricci, Emiliano P., Ohlmann, Théophile, Darlix, Jean-Luc, López-Lastra, Marcelo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937818/
https://ncbi.nlm.nih.gov/pubmed/20660206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01270-10
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky