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Tropism of and Innate Immune Responses to the Novel Human Betacoronavirus Lineage C Virus in Human Ex Vivo Respiratory Organ Cultures

Since April 2012, there have been 17 laboratory-confirmed human cases of respiratory disease associated with newly recognized human betacoronavirus lineage C virus EMC (HCoV-EMC), and 7 of them were fatal. The transmissibility and pathogenesis of HCoV-EMC remain poorly understood, and elucidating it...

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Detalhes bibliográficos
Main Authors: Chan, Renee W. Y., Chan, Michael C. W., Agnihothram, Sudhakar, Chan, Louisa L. Y., Kuok, Denise I. T., Fong, Joanne H. M., Guan, Y., Poon, Leo L. M., Baric, Ralph S., Nicholls, John M., Peiris, J. S. Malik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676115/
https://ncbi.nlm.nih.gov/pubmed/23552422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00009-13
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