Tropism of and Innate Immune Responses to the Novel Human Betacoronavirus Lineage C Virus in Human Ex Vivo Respiratory Organ Cultures

Since April 2012, there have been 17 laboratory-confirmed human cases of respiratory disease associated with newly recognized human betacoronavirus lineage C virus EMC (HCoV-EMC), and 7 of them were fatal. The transmissibility and pathogenesis of HCoV-EMC remain poorly understood, and elucidating it...

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Autores principales: Chan, Renee W. Y., Chan, Michael C. W., Agnihothram, Sudhakar, Chan, Louisa L. Y., Kuok, Denise I. T., Fong, Joanne H. M., Guan, Y., Poon, Leo L. M., Baric, Ralph S., Nicholls, John M., Peiris, J. S. Malik
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676115/
https://ncbi.nlm.nih.gov/pubmed/23552422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00009-13
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