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Tropism and innate host responses of a novel avian influenza A H7N9 virus: an analysis of ex-vivo and in-vitro cultures of the human respiratory tract

BACKGROUND: Since March, 2013, an avian-origin influenza A H7N9 virus has caused severe pneumonia in China. The aim of this study was to investigate the pathogenesis of this new virus in human beings. METHODS: We obtained ex-vivo cultures of the human bronchus, lung, nasopharynx, and tonsil and in-v...

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Detalhes bibliográficos
Publicado no:Lancet Respir Med
Principais autores: Chan, Michael CW, Chan, Renee WY, Chan, Louisa LY, Mok, Chris KP, Hui, Kenrie PY, Fong, Joanne HM, Tao, Kin P, Poon, Leo LM, Nicholls, John M, Guan, Y, Peiris, JS Malik
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164816/
https://ncbi.nlm.nih.gov/pubmed/24461614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2213-2600(13)70138-3
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