Tropism and innate host responses of a novel avian influenza A H7N9 virus: an analysis of ex-vivo and in-vitro cultures of the human respiratory tract

BACKGROUND: Since March, 2013, an avian-origin influenza A H7N9 virus has caused severe pneumonia in China. The aim of this study was to investigate the pathogenesis of this new virus in human beings. METHODS: We obtained ex-vivo cultures of the human bronchus, lung, nasopharynx, and tonsil and in-v...

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Published in:Lancet Respir Med
Main Authors: Chan, Michael CW, Chan, Renee WY, Chan, Louisa LY, Mok, Chris KP, Hui, Kenrie PY, Fong, Joanne HM, Tao, Kin P, Poon, Leo LM, Nicholls, John M, Guan, Y, Peiris, JS Malik
Format: Artigo
Language:Inglês
Published: Elsevier Ltd. 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164816/
https://ncbi.nlm.nih.gov/pubmed/24461614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2213-2600(13)70138-3
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