Tropism of and Innate Immune Responses to the Novel Human Betacoronavirus Lineage C Virus in Human Ex Vivo Respiratory Organ Cultures

Since April 2012, there have been 17 laboratory-confirmed human cases of respiratory disease associated with newly recognized human betacoronavirus lineage C virus EMC (HCoV-EMC), and 7 of them were fatal. The transmissibility and pathogenesis of HCoV-EMC remain poorly understood, and elucidating it...

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Bibliographic Details
Main Authors: Chan, Renee W. Y., Chan, Michael C. W., Agnihothram, Sudhakar, Chan, Louisa L. Y., Kuok, Denise I. T., Fong, Joanne H. M., Guan, Y., Poon, Leo L. M., Baric, Ralph S., Nicholls, John M., Peiris, J. S. Malik
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676115/
https://ncbi.nlm.nih.gov/pubmed/23552422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00009-13
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