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HIV-1 Vpu Does Not Degrade Interferon Regulatory Factor 3
It has been reported that HIV-1 Vpu mediates the degradation of interferon regulatory factor 3 (IRF-3) to avoid innate immune sensing. Here, we show that Vpu does not deplete IRF-3 from transfected cell lines or HIV-1-infected primary cells. Furthermore, the Vpu-dependent suppression of beta interfe...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3676088/ https://ncbi.nlm.nih.gov/pubmed/23552418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00526-13 |
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