5' Nucleotide sequences influence serum-modulated expression of a human dihydrofolate reductase minigene.

Human dihydrofolate reductase (DHFR) gene sequences were isolated from DHFR gene-amplified breast cancer cell line MCF-7. These genomic sequences plus human DHFR cDNA sequences were used to construct a DHFR minigene. Calcium phosphate-mediated transfer of minigene DNA into DHFR gene-deleted Chinese...

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Bibliographic Details
Main Authors: Goldsmith, M E, Beckman, C A, Cowan, K H
Format: Artigo
Language:Inglês
Published: 1986
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC367588/
https://ncbi.nlm.nih.gov/pubmed/3022136
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