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Nucleolin Mediates MicroRNA-directed CSF-1 mRNA Deadenylation but Increases Translation of CSF-1 mRNA

CSF-1 mRNA 3′UTR contains multiple unique motifs, including a common microRNA (miRNA) target in close proximity to a noncanonical G-quadruplex and AU-rich elements (AREs). Using a luciferase reporter system fused to CSF-1 mRNA 3′UTR, disruption of the miRNA target region, G-quadruplex, and AREs toge...

詳細記述

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書誌詳細
主要な著者: Woo, Ho-Hyung, Baker, Terri, Laszlo, Csaba, Chambers, Setsuko K.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Biochemistry and Molecular Biology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675821/
https://ncbi.nlm.nih.gov/pubmed/23471483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.025288
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