Quantitative Proteomics Demonstrates That the RNA Polymerase II Subunits Rpb4 and Rpb7 Dissociate during Transcriptional Elongation

Eukaryotic RNA polymerase II (RNAPII) is a 12-subunit enzyme that is responsible for the transcription of messenger RNA. Two of the subunits of RNA polymerase II, Rpb4 and Rpb7, have been shown to dissociate from the enzyme under a number of specific laboratory conditions. However, a biological cont...

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Библиографические подробности
Главные авторы: Mosley, Amber L., Hunter, Gerald O., Sardiu, Mihaela E., Smolle, Michaela, Workman, Jerry L., Florens, Laurence, Washburn, Michael P.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Biochemistry and Molecular Biology 2013
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Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675811/
https://ncbi.nlm.nih.gov/pubmed/23418395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.024034
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