Llwytho...

Deacetylase inhibitors dissociate the histone-targeting ING2 subunit from the Sin3 complex

Histone deacetylase (HDAC) inhibitors are in clinical development for several diseases, including cancers and neurodegenerative disorders. HDACs1 and 2 are among the targets of these inhibitors and are part of multisubunit protein complexes. HDAC inhibitors (HDACi) block the activity of HDACs by che...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Smith, Karen T., Martin-Brown, Skylar A., Florens, Laurence, Washburn, Michael P., Workman, Jerry L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819981/
https://ncbi.nlm.nih.gov/pubmed/20142042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2009.12.010
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