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Gcn5 regulates the dissociation of SWI/SNF from chromatin by acetylation of Swi2/Snf2
The positive link between the SWI/SNF and the Gcn5 histone acetyltransferase in transcriptional activation has been well described. Here we report an inhibitory role for Gcn5 in SWI/SNF targeting. We demonstrate that Gcn5-containing complexes directly acetylate the Snf2 subunit of the SWI/SNF comple...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3003194/ https://ncbi.nlm.nih.gov/pubmed/21159817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1979710 |
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