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Gcn5 regulates the dissociation of SWI/SNF from chromatin by acetylation of Swi2/Snf2

The positive link between the SWI/SNF and the Gcn5 histone acetyltransferase in transcriptional activation has been well described. Here we report an inhibitory role for Gcn5 in SWI/SNF targeting. We demonstrate that Gcn5-containing complexes directly acetylate the Snf2 subunit of the SWI/SNF comple...

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Detalhes bibliográficos
Main Authors: Kim, Jeong-Hoon, Saraf, Anita, Florens, Laurence, Washburn, Michael, Workman, Jerry L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003194/
https://ncbi.nlm.nih.gov/pubmed/21159817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1979710
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