The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF

The histone regulatory (HIR) and histone promoter control (HPC) repressor proteins regulate three of the four histone gene loci during the Saccharomyces cerevisiae cell cycle. Here, we demonstrate that Hir1, Hir2, Hir3, and Hpc2 proteins form a stable HIR repressor complex. The HIR complex promotes...

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Bibliographic Details
Main Authors: Prochasson, Philippe, Florens, Laurence, Swanson, Selene K., Washburn, Michael P., Workman, Jerry L.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2005
Subjects:
Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276727/
https://ncbi.nlm.nih.gov/pubmed/16264190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1341105
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