HP1 promotes tumor suppressor BRCA1 functions during the DNA damage response

The DNA damage response (DDR) involves both the control of DNA damage repair and signaling to cell cycle checkpoints. Therefore, unraveling the underlying mechanisms of the DDR is important for understanding tumor suppression and cellular resistance to clastogenic cancer therapeutics. Because the DD...

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Bibliografiska uppgifter
Huvudupphovsmän: Lee, Young-Ho, Kuo, Ching-Ying, Stark, Jeremy M., Shih, Hsiu-Ming, Ann, David K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2013
Ämnen:
Genome Integrity, Repair and Replication
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675466/
https://ncbi.nlm.nih.gov/pubmed/23589625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt231
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